• Abstract
• Full-Text PDF [160 KB]

• Article Statistics
• Google Scholar
• Order Reprints

• Cite this article
• Export to BibTeX
• Export to EndNote

• [+] on DOAJ
• Rizk, NM.H.
• Abbas, SS.
• Hamza, SM.
• Hamza, SM.
• Abd EL-Karem, YM.
• [+] on Google Scholar
• Rizk, NM.H.
• Abbas, SS.
• Hamza, SM.
• Hamza, SM.
• Abd EL-Karem, YM.
• [+] on PubMed
• Rizk, NM.H.
• Abbas, SS.
• Hamza, SM.
• Hamza, SM.
• Abd EL-Karem, YM.

•  CiteULike
•  Connotea
•  Facebook
•  Mendeley
•  Twitter

This article is

• freely available
• re-usable

Sensors 2009, 9(3), 1860-1875; doi:10.3390/s90301860

Article

Thiopental and Phenytoin as Novel Ionophores for Potentiometric Determination of Lead (II) Ions

Nashwa M.H. Rizk^1,* , Samah S. Abbas² , Salem M. Hamza³ , Salem M. Hamza³  and Yasser M. Abd EL-Karem³

¹ Environmental Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), Minufiya University, Sadat City, Egypt ² 2 Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt ³ Chemistry Department, Faculty of Sciences, Minufiya University, Egypt

* Author to whom correspondence should be addressed.

Received: 20 January 2009; in revised form: 23 February 2009 / Accepted: 9 March 2009 / Published: 13 March 2009

(This article belongs to the Section Chemical Sensors)

Download PDF Full-Text [160 KB, uploaded 13 March 2009 14:40 CET]

Abstract: Two novel polymeric membrane sensors for the analysis of Pb(II) have been developed based ontwo therapeutic drugs, thiopental (TP) and phenytoin (PT) as two new ionophores and potassium tetrakis(p-chlorophenyl) borate (KTpClPB) as a lipophilic additive, in plasticized PVC membranes. The sensors show a Nernstian response for Pb(II) ions over the wide concentration ranges of 1×10^-2 - 7×10^-6 M and 1×10^-2 - 8×10^-6 M for the sensors based on thiopental and phenytoin, respectively. The proposed sensors have a fast response time and can be used for more than nine weeks without any considerable divergence in potentials. The sensors exhibit comparatively good selectivity with respect to alkaline, alkaline earth and some transition and heavy metal ions. They were employed for direct determination of lead in solder alloys and in galena rocks with a good agreement with the obtained results by atomic absorption spectroscopy.

Keywords: Lead (II); Thiopental; Phenytoin; Galena rocks; Solder alloys

Article Statistics

Cite This Article