Next Article in Journal
Observing and Studying Extreme Low Pressure Events with Altimetry
Previous Article in Journal
Improvement of the Accuracy of InSAR Image Co-Registration Based On Tie Points – A Review
Article Menu

Export Article

Open AccessArticle
Sensors 2009, 9(3), 1295-1305; doi:10.3390/s90301295

Role of SAM Chain Length in Enhancing the Sensitivity of Nanopillar Modified Electrodes for Glucose Detection

1
Micro/Nano Bioengineering Lab, The University of Georgia, USA
2
Faculty of Engineering, The University of Georgia, USA
3
Bioengineering, Electrical & Computer Engineering, Clemson University, USA
4
Institute for Biological Interfaces of Engineering, Clemson University, USA
*
Author to whom correspondence should be addressed.
Received: 27 January 2009 / Revised: 24 February 2009 / Accepted: 24 February 2009 / Published: 26 February 2009
View Full-Text   |   Download PDF [464 KB, uploaded 21 June 2014]   |  

Abstract

In this report, alkanethiol self assembled monolayers (SAM) with two different chain lengths were used to immobilize the functionalizing enzyme (glucose oxidase) onto gold nanopillar modified electrodes and the electrochemical processes of these functionalized electrodes in glucose detection were investigated. First, the formation of these SAMs on the nanopillar modified electrodes was characterized by the cyclic voltammetry and electrochemical impedance spectroscopy techniques, and then the detection sensitivity of these functionalized electrodes to glucose was evaluated by the amperometry technique. Results showed that the SAM of alkanethiols with a longer chain length resulted in a higher degree of surface coverage with less defect and a higher electron transfer resistance, whereas the SAM of alkanethiols with a shorter chain length gave rise to a higher detection sensitivity to glucose. This study sheds some new insight into how to enhance the sensing performance of nanopillar modified electrodes. View Full-Text
Keywords: Gold nanopillar modified electrodes; self assembled monolayer; alkanethiols; electrochemical processes; glucose detection; biosensors Gold nanopillar modified electrodes; self assembled monolayer; alkanethiols; electrochemical processes; glucose detection; biosensors
Figures

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Anandan, V.; Gangadharan, R.; Zhang, G. Role of SAM Chain Length in Enhancing the Sensitivity of Nanopillar Modified Electrodes for Glucose Detection. Sensors 2009, 9, 1295-1305.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top