Sensors 2008, 8(7), 4201-4212; doi:10.3390/s8074201
Article

Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes

Departamento de Química, Área de Química Analítica, Facultad de Ciencias, Universidad de Burgos, Plaza Misael Bañuelos s/n, E-09001 Burgos, Spain
* Author to whom correspondence should be addressed.
Received: 5 June 2008; in revised form: 25 June 2008 / Accepted: 10 July 2008 / Published: 15 July 2008
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Abstract: This paper describes a procedure that has been optimized for the determination of lamotrigine by Differential Pulse Adsorptive Stripping Voltammetry (DPAdSV) using carbon screen-printed electrodes (CSPE) and mercury coated carbon screen-printed electrodes. Selection of the experimental parameters was made using experimental design methodology. The detection limit found was 5.0 x 10-6 M and 2.0 x 10-6 M for the non modified and Hg modified CSPE, respectively. In terms of reproducibility, the precision of the above mentioned methods was calculated in %RSD values at 9.83% for CSPE and 2.73% for Hg-CSPE. The Hg-coated CSPEs developed in this work were successfully applied in the determination of lamotrigine in pharmaceutical preparations.
Keywords: lamotrigine; screen-printed electrodes; differential pulse adsorptive stripping voltammetry.

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MDPI and ACS Style

Domínguez-Renedo, O.; Calvo, M.E.B.; Arcos-Martínez, M.J. Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes. Sensors 2008, 8, 4201-4212.

AMA Style

Domínguez-Renedo O, Calvo MEB, Arcos-Martínez MJ. Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes. Sensors. 2008; 8(7):4201-4212.

Chicago/Turabian Style

Domínguez-Renedo, Olga; Calvo, M. E.B.; Arcos-Martínez, M. J. 2008. "Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes." Sensors 8, no. 7: 4201-4212.

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