CiteULike
Facebook
Mendeley
Twitter
This article is- freely available
- re-usable
Sensors 2008, 8(7), 4201-4212; doi:10.3390/s8074201
Article
Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes
Departamento de Química, Área de Química Analítica, Facultad de Ciencias, Universidad de Burgos, Plaza Misael Bañuelos s/n, E-09001 Burgos, Spain
* Author to whom correspondence should be addressed.
Received: 5 June 2008; in revised form: 25 June 2008 / Accepted: 10 July 2008 / Published: 15 July 2008
Download PDF Full-Text [98 KB, uploaded 16 September 2008 11:02 CEST]
Abstract: This paper describes a procedure that has been optimized for the determination of lamotrigine by Differential Pulse Adsorptive Stripping Voltammetry (DPAdSV) using carbon screen-printed electrodes (CSPE) and mercury coated carbon screen-printed electrodes. Selection of the experimental parameters was made using experimental design methodology. The detection limit found was 5.0 x 10-6 M and 2.0 x 10-6 M for the non modified and Hg modified CSPE, respectively. In terms of reproducibility, the precision of the above mentioned methods was calculated in %RSD values at 9.83% for CSPE and 2.73% for Hg-CSPE. The Hg-coated CSPEs developed in this work were successfully applied in the determination of lamotrigine in pharmaceutical preparations.
Keywords: lamotrigine; screen-printed electrodes; differential pulse adsorptive stripping voltammetry.
Article Statistics
Click here to load and display the download statistics.Cite This Article
MDPI and ACS Style
Domínguez-Renedo, O.; Calvo, M.E.B.; Arcos-Martínez, M.J. Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes. Sensors 2008, 8, 4201-4212.
AMA StyleDomínguez-Renedo O, Calvo MEB, Arcos-Martínez MJ. Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes. Sensors. 2008; 8(7):4201-4212.
Chicago/Turabian StyleDomínguez-Renedo, Olga; Calvo, M. E.B.; Arcos-Martínez, M. J. 2008. "Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes." Sensors 8, no. 7: 4201-4212.