Next Article in Journal
Modeling Forest Productivity Using Envisat MERIS Data
Next Article in Special Issue
Thermally Stable Merocyanine Form of Photochromic Spiropyran with Aluminum Ion as a Reversible Photo-driven Sensor in Aqueous Solution
Previous Article in Journal
Determination of DPPH Radical Oxidation Caused by Methanolic Extracts of Some Microalgal Species by Linear Regression Analysis of Spectrophotometric Measurements
Previous Article in Special Issue
Cross-Reactive Sensor Array for Metal Ion Sensing Based on Fluorescent SAMs
Article Menu

Export Article

Open AccessArticle
Sensors 2007, 7(10), 2096-2114; doi:10.3390/s7102096

Synthesis, Characterization and Metal Ion Detection of Novel Fluoroionophores Based on Heterocyclic Substituted Alanines

Centro de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal
REQUIMTE, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Monte de Caparica, Portugal
Author to whom correspondence should be addressed.
Received: 19 September 2007 / Accepted: 27 September 2007 / Published: 3 October 2007
(This article belongs to the Special Issue Supramolecular Sensors)
View Full-Text   |   Download PDF [580 KB, uploaded 21 June 2014]   |  


The synthesis of new fluorescent probes containing the thiophene andbenzoxazole moieties combined with an alanine residue is described. The resulting highlyfluorescent heterocyclic alanine derivatives respond via a quenching effect, withparamagnetic Cu(II) and Ni(II) metal ions and with diamagnetic Hg(II), as shown by theabsorption and steady-state fluorescence spectroscopy studies. The formation ofmononuclear or dinuclear metal complexes was postulated based on the presence of thefree carboxylic acid as binding site and also with the interaction with the donor atoms inthe chromophore. Interaction with other important biological metal ions such as Zn(II),Ca(II) and Na(I) was also explored. View Full-Text
Keywords: Benzoxazole; Thiophene; Amino acids; Fluorescence; Fluorescent probes. Benzoxazole; Thiophene; Amino acids; Fluorescence; Fluorescent probes.

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Costa, S.P.G.; Oliveira, E.; Lodeiro, C.; Raposo, M.M.M. Synthesis, Characterization and Metal Ion Detection of Novel Fluoroionophores Based on Heterocyclic Substituted Alanines. Sensors 2007, 7, 2096-2114.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top