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Sensors 2003, 3(10), 443-450; doi:10.3390/s31000443

Determination of Dopamine in the Presence of Ascorbic Acid using Poly (Acridine red) Modified Glassy Carbon Electrode

School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China
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Received: 6 August 2003 / Accepted: 25 September 2003 / Published: 31 October 2003
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Abstract

Poly (acridine red) modified glassy carbon electrode was used for the detection of dopamine in the presence of ascorbic acid in a pH 7.4 phosphate buffer solutions (PBS) by cyclic voltammetry and differential pulse voltammetry. The major difficulty of the overlapped oxidation potential of ascorbic acid could be overcome through the distinct attractive ability of poly (acridine red) film to cationic dopamine and anionic ascorbic acid. The results showed that the dopamine anodic peak current and the concentration of dopamine had a linear relationship in the range of 1.0×10-7 ~ 1.0×10-4 mol dm-3. The detection limit (S/N=3) obtained by differential pulse voltammetry was 1.0×10-9 mol dm-3. The relative standard deviation of 10 successive scans was 2.07 % for 1.0×10-6 mol dm-3 DA. Ascorbic acid had hardly interference with the determination of dopamine. The proposed method exhibits good recovery and reproducibility. View Full-Text
Keywords: Glassy carbon electrode; Chemically Modified electrode; Dopamine; Ascorbic Acid; Acridine red Glassy carbon electrode; Chemically Modified electrode; Dopamine; Ascorbic Acid; Acridine red
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MDPI and ACS Style

Zhang, Y.; Jin, G.; Wang, Y.; Yang, Z. Determination of Dopamine in the Presence of Ascorbic Acid using Poly (Acridine red) Modified Glassy Carbon Electrode. Sensors 2003, 3, 443-450.

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