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• Guo-ping, C
• Rong-min, X
• Jun, G
• Wen-de, S
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• Rong-min, X
• Jun, G
• Wen-de, S
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• Rong-min, X
• Jun, G
• Wen-de, S

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Sensors 2002, 2(11), 447-454; doi:10.3390/s21100447

Article

Study on pH Effect in Process of an Entero-gastric Fiber-optic Sensor Design

Chen Guo-ping ^1,* , Xia Rong-min ¹ , Gong Jun ²  and Shou Wen-de ¹

¹ Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China ² Department of Digestion, Second Hospital of Xi’an Jiaotong University, Xi’an 710004,China

* Author to whom correspondence should be addressed.

Received: 28 October 2002 / Accepted: 15 November 2002 / Published: 30 November 2002

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Abstract: The pH effect on design of a fiber optic sensor newly developed for monitoring entero-gastric reflux is investigated. The research has been carried out by utilizing the sensor to measure characteristic absorption of bilirubin standard solution (used as a calibrator) at different pH values from about 1 to 8. The results show explicitly that the estimation error according to the calibration curves with pH <7 is significantly lower than that at alkaline pH values. Compared with the in vitro experimental data, the optimum pH range for entero-gastric reflux analysis is proposed to be between 5-6. The possible reasons for estimation error of the fiber optic sensor are given in detail.

Keywords: Fiber optic sensor; Bilirubin; pH; Entero-gastric reflux

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