Sensors 2002, 2(11), 436-446; doi:10.3390/s21100436
Article

Mathematical Modelling of the Electrode Process of Azithromycin Using Cyclic Voltammetry at Hanging Mercury Drop Electrode

Reyad A. Shawabkeh 1,* email and Maha F. Tutunji 2
1 Department of Chemical Engineering, Mutah University, AL-Karak, Jordan 2 Department of Chemistry-University of Jordan, Director of Pharmaceutical Research unit-Royal Scientific Society, Amman, Jordan
* Author to whom correspondence should be addressed.
Received: 9 September 2002 / Accepted: 20 October 2002 / Published: 30 November 2002
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Abstract: A theoretical treatment is presented to predict the kinetic behaviour of azithromycin at the surface of hanging mercury drop electrode using cyclic voltammetry. A model is developed to incorporate the occurrence of adsorption of the oxidized and reduced species of azithromycin at the surface of mercury drop electrode. An analytical solution was obtained using MATHEMATICA (V-3, Wolfram Research, Inc.) to predict the cyclic voltammetric profiles by calculating the currents resulting after applying variable potentials ranging –1.9 to –1.3 V versus Ag/AgCl. Simulation runs at different initial concentrations of azithromycin and different scan rates showed good agreement with experimental findings. However, this model should be modified to describe a multilayer adsorption with irreversible electrochemical reaction.
Keywords: Adsorption; Azithromycin; Cyclic Voltammetry; Mercury Drop Electrode

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MDPI and ACS Style

Shawabkeh, R.A.; Tutunji, M.F. Mathematical Modelling of the Electrode Process of Azithromycin Using Cyclic Voltammetry at Hanging Mercury Drop Electrode. Sensors 2002, 2, 436-446.

AMA Style

Shawabkeh RA, Tutunji MF. Mathematical Modelling of the Electrode Process of Azithromycin Using Cyclic Voltammetry at Hanging Mercury Drop Electrode. Sensors. 2002; 2(11):436-446.

Chicago/Turabian Style

Shawabkeh, Reyad A.; Tutunji, Maha F. 2002. "Mathematical Modelling of the Electrode Process of Azithromycin Using Cyclic Voltammetry at Hanging Mercury Drop Electrode." Sensors 2, no. 11: 436-446.

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