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Sensors 2017, 17(2), 236; doi:10.3390/s17020236

Fabrication of Annealed Gold Nanostructures on Pre-Treated Glow-Discharge Cleaned Glasses and Their Used for Localized Surface Plasmon Resonance (LSPR) and Surface Enhanced Raman Spectroscopy (SERS) Detection of Adsorbed (Bio)molecules

1
Laboratory of Nanotechnology, Instrumentation and Optics, UMR-CNRS 6281, Institute Charles Delaunay, University of Champagne, University of Technology of Troyes, 12 Rue Marie Curie CS 42060, 10004 Troyes CEDEX, France
2
Laboratory Interdisciplinaire Carnot de Bourgogne (ICB), UMR-CNRS 6303, University of Bourgogne Franche-Comte, 9 Avenue Alain Savary, 21078 Dijon CEDEX, France
*
Author to whom correspondence should be addressed.
Academic Editor: Laura M. Lechuga
Received: 21 November 2016 / Revised: 4 January 2017 / Accepted: 18 January 2017 / Published: 26 January 2017
(This article belongs to the Special Issue Last Advances in Nanoplasmonics Biosensors)
View Full-Text   |   Download PDF [3328 KB, uploaded 26 January 2017]   |  

Abstract

Metallic nanoparticles are considered as active supports in the development of specific chemical or biological biosensors. Well-organized nanoparticles can be prepared either through expensive (e.g., electron beam lithography) or inexpensive (e.g., thermal synthesis) approaches where different shapes of nanoparticles are easily obtained over large solid surfaces. Herein, the authors propose a low-cost thermal synthesis of active plasmonic nanostructures on thin gold layers modified glass supports after 1 h holding on a hot plate (~350 °C). The resulted annealed nanoparticles proved a good reproducibility of localized surface plasmon resonance (LSPR) and surface enhanced Raman spectroscopy (SERS) optical responses and where used for the detection of low concentrations of two model (bio)chemical molecules, namely the human cytochrome b5 (Cyt-b5) and trans-1,2-bis(4-pyridyl)ethylene (BPE). View Full-Text
Keywords: annealed gold nanostructures; (bio)functionalization; improved LSPR and SERS sensitivity; human cytochrome b5; trans-1,2-bis(4-pyridyl)ethylene annealed gold nanostructures; (bio)functionalization; improved LSPR and SERS sensitivity; human cytochrome b5; trans-1,2-bis(4-pyridyl)ethylene
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Ionescu, R.E.; Aybeke, E.N.; Bourillot, E.; Lacroute, Y.; Lesniewska, E.; Adam, P.-M.; Bijeon, J.-L. Fabrication of Annealed Gold Nanostructures on Pre-Treated Glow-Discharge Cleaned Glasses and Their Used for Localized Surface Plasmon Resonance (LSPR) and Surface Enhanced Raman Spectroscopy (SERS) Detection of Adsorbed (Bio)molecules. Sensors 2017, 17, 236.

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