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Sensors 2017, 17(12), 2752; doi:10.3390/s17122752

Effect of Shot Noise on Simultaneous Sensing in Frequency Division Multiplexed Diffuse Optical Tomographic Imaging Process

1
Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Korea
2
Tu & Yuen Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA 92697, USA
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 30 September 2017 / Revised: 17 November 2017 / Accepted: 23 November 2017 / Published: 28 November 2017
(This article belongs to the Special Issue Novel Sensors for Bioimaging)
View Full-Text   |   Download PDF [3002 KB, uploaded 28 November 2017]   |  

Abstract

Diffuse optical tomography (DOT) has been studied for use in the detection of breast cancer, cerebral oxygenation, and cognitive brain signals. As optical imaging studies have increased significantly, acquiring imaging data in real time has become increasingly important. We have developed frequency-division multiplexing (FDM) DOT systems to analyze their performance with respect to acquisition time and imaging quality, in comparison with the conventional time-division multiplexing (TDM) DOT. A large tomographic area of a cylindrical phantom 60 mm in diameter could be successfully reconstructed using both TDM DOT and FDM DOT systems. In our experiment with 6 source-detector (S-D) pairs, the TDM DOT and FDM DOT systems required 6.18 and 1 s, respectively, to obtain a single tomographic data set. While the absorption coefficient of the reconstruction image was underestimated in the case of the FDM DOT, we experimentally confirmed that the abnormal region can be clearly distinguished from the background phantom using both methods. View Full-Text
Keywords: shot noise; diffuse optical tomography; time-division multiplexing; frequency-division multiplexing shot noise; diffuse optical tomography; time-division multiplexing; frequency-division multiplexing
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Jang, H.; Lim, G.; Hong, K.-S.; Cho, J.; Gulsen, G.; Kim, C.-S. Effect of Shot Noise on Simultaneous Sensing in Frequency Division Multiplexed Diffuse Optical Tomographic Imaging Process. Sensors 2017, 17, 2752.

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