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Sensors 2016, 16(6), 914; doi:10.3390/s16060914

Characterization of a Functional Hydrogel Layer on a Silicon-Based Grating Waveguide for a Biochemical Sensor

1
School of Electronic and Electric Engineering, Hongik University, Seoul 121-791, Korea
2
Department of Neurology, Molecular Imaging and Neurovascular Research (MINER) Laboratory, Dongguk University Ilsan Hospital, Goyang 10326, Korea
*
Authors to whom correspondence should be addressed.
Academic Editor: Alexandre François
Received: 7 April 2016 / Revised: 7 June 2016 / Accepted: 15 June 2016 / Published: 18 June 2016
(This article belongs to the Special Issue Label-Free Optical Biosensors)
View Full-Text   |   Download PDF [3788 KB, uploaded 18 June 2016]   |  

Abstract

We numerically demonstrated the characteristics of a functional hydrogel layer on a silicon-based grating waveguide for a simple, cost-effective refractive index (RI) biochemical sensor. The RI of the functional hydrogel layer changes when a specific biochemical interaction occurs between the hydrogel-linked receptors and injected ligand molecules. The transmission spectral profile of the grating waveguide shifts depends on the amount of RI change caused by the functional layer. Our characterization includes the effective RI change caused by the thickness, functional volume ratio, and functional strength of the hydrogel layer. The results confirm the feasibility of, and set design rules for, hydrogel-assisted silicon-based grating waveguides. View Full-Text
Keywords: waveguides; diffraction gratings; biological sensing and sensors; optical sensing and sensors waveguides; diffraction gratings; biological sensing and sensors; optical sensing and sensors
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Hong, Y.-S.; Kim, J.; Sung, H.-K. Characterization of a Functional Hydrogel Layer on a Silicon-Based Grating Waveguide for a Biochemical Sensor. Sensors 2016, 16, 914.

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