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Sensors 2016, 16(6), 809; doi:10.3390/s16060809

A Wireless Pressure Sensor Integrated with a Biodegradable Polymer Stent for Biomedical Applications

1
MEMS and Nanotechnology Laboratory, Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea
2
Department of Defense Science and Technology, Gwangju University, Gwangju 61743, Korea
3
CGBio Co. Ltd., Jangseong-gun 57248, Korea
4
Department of Nature-Inspired Nanoconvergence Systems, Nanoconvergence Mechanical System Division, Korea Institute of Machinery and Materials (KIMM), Daejeon 34103, Korea
*
Author to whom correspondence should be addressed.
Academic Editor: Panicos Kyriacou
Received: 31 March 2016 / Revised: 23 May 2016 / Accepted: 26 May 2016 / Published: 2 June 2016
(This article belongs to the Collection Sensors for Globalized Healthy Living and Wellbeing)
View Full-Text   |   Download PDF [3832 KB, uploaded 2 June 2016]   |  

Abstract

This paper describes the fabrication and characterization of a wireless pressure sensor for smart stent applications. The micromachined pressure sensor has an area of 3.13 × 3.16 mm2 and is fabricated with a photosensitive SU-8 polymer. The wireless pressure sensor comprises a resonant circuit and can be used without the use of an internal power source. The capacitance variations caused by changes in the intravascular pressure shift the resonance frequency of the sensor. This change can be detected using an external antenna, thus enabling the measurement of the pressure changes inside a tube with a simple external circuit. The wireless pressure sensor is capable of measuring pressure from 0 mmHg to 230 mmHg, with a sensitivity of 0.043 MHz/mmHg. The biocompatibility of the pressure sensor was evaluated using cardiac cells isolated from neonatal rat ventricular myocytes. After inserting a metal stent integrated with the pressure sensor into a cardiovascular vessel of an animal, medical systems such as X-ray were employed to consistently monitor the condition of the blood vessel. No abnormality was found in the animal blood vessel for approximately one month. Furthermore, a biodegradable polymer (polycaprolactone) stent was fabricated with a 3D printer. The polymer stent exhibits better sensitivity degradation of the pressure sensor compared to the metal stent. View Full-Text
Keywords: pressure sensor; LC circuit; SU-8; wireless sensing; polymer stent pressure sensor; LC circuit; SU-8; wireless sensing; polymer stent
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Park, J.; Kim, J.-K.; Patil, S.J.; Park, J.-K.; Park, S.; Lee, D.-W. A Wireless Pressure Sensor Integrated with a Biodegradable Polymer Stent for Biomedical Applications. Sensors 2016, 16, 809.

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