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Sensors 2016, 16(11), 1785; doi:10.3390/s16111785

Detection of Copper(II) Ions Using Glycine on Hydrazine-Adsorbed Gold Nanoparticles via Raman Spectroscopy

1
Department of Chemistry, Soongsil University, Seoul 156-743, Korea
2
Department of Information Communication, Materials, and Chemistry Convergence Technology, Soongsil University, Seoul 156-743, Korea
*
Author to whom correspondence should be addressed.
Academic Editors: Jong Seung Kim and Min Hee Lee
Received: 19 August 2016 / Revised: 7 October 2016 / Accepted: 13 October 2016 / Published: 26 October 2016
(This article belongs to the Special Issue Colorimetric and Fluorescent Sensor)
View Full-Text   |   Download PDF [2837 KB, uploaded 26 October 2016]   |  

Abstract

A facile, selective, and sensitive detection method for the Cu2+ ions in environmental and biological solutions has been newly developed by observing the unique CN stretching peaks at ~2108 cm−1 upon the dissociative adsorption of glycine (GLY) in hydrazine buffer on gold nanoparticles (AuNPs). The relative abundance of Cu species on AuNPs was identified from X-ray photoelectron spectroscopy analysis. UV-Vis spectra also indicated that the Au particles aggregated to result in the color change owing to the destabilization induced by the GLY-Cu2+ complex. The CN stretching band at ~2108 cm−1 could be observed to indicate the formation of the CN species from GLY on the hydrazine-covered AuNP surfaces. The other ions of Fe3+, Fe2+, Hg2+, Mg2+, Mn2+, Ni2+, Zn2+, Cr3+, Co2+, Cd2+, Pb2+, Ca2+, NH4+, Na+, and K+ at high concentrations of 50 µM did not produce such spectral changes. The detection limit based on the CN band for the determination of the Cu2+ ion could be estimated to be as low as 500 nM in distilled water and 1 µM in river water, respectively. We attempted to apply our method to estimate intracellular ion detection in cancer cells for more practical purposes. View Full-Text
Keywords: Cu(II); Raman spectroscopy; C≡N stretching mode; gold nanoparticles; glycine; intracellular imaging Cu(II); Raman spectroscopy; C≡N stretching mode; gold nanoparticles; glycine; intracellular imaging
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Ly, N.H.; Seo, C.; Joo, S.-W. Detection of Copper(II) Ions Using Glycine on Hydrazine-Adsorbed Gold Nanoparticles via Raman Spectroscopy. Sensors 2016, 16, 1785.

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