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Sensors 2015, 15(2), 3706-3720; doi:10.3390/s150203706

Plasmonic Gold Nanostars for Multi-Modality Sensing and Diagnostics

1
Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA
2
Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
3
Department of Chemistry, Duke University, Durham, NC 27708, USA
4
Department of Radiology & Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, NC 27510, USA
*
Author to whom correspondence should be addressed.
Received: 13 January 2015 / Accepted: 30 January 2015 / Published: 5 February 2015
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Abstract

Gold nanostars (AuNSs) are unique systems that can provide a novel multifunctional nanoplatform for molecular sensing and diagnostics. The plasmonic absorption band of AuNSs can be tuned to the near infrared spectral range, often referred to as the “tissue optical window”, where light exhibits minimal absorption and deep penetration in tissue. AuNSs have been applied for detecting disease biomarkers and for biomedical imaging using multi-modality methods including surface-enhanced Raman scattering (SERS), two-photon photoluminescence (TPL), magnetic resonance imaging (MRI), positron emission tomography (PET), and X-ray computer tomography (CT) imaging. In this paper, we provide an overview of the recent development of plasmonic AuNSs in our laboratory for biomedical applications and highlight their potential for future translational medicine as a multifunctional nanoplatform. View Full-Text
Keywords: gold nanostars; plasmonics; multifunctional; sensing gold nanostars; plasmonics; multifunctional; sensing
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Liu, Y.; Yuan, H.; Kersey, F.R.; Register, J.K.; Parrott, M.C.; Vo-Dinh, T. Plasmonic Gold Nanostars for Multi-Modality Sensing and Diagnostics. Sensors 2015, 15, 3706-3720.

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