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Sensors 2014, 14(7), 11672-11681; doi:10.3390/s140711672

In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures

1
Department of Electronic Engineering, University of Tor Vergata, via del Politecnico, 1-00133 Rome, Italy
2
Department of Civil Engineering and Computer Science, University of Tor Vergata, via del Politecnico, 1-00133 Rome, Italy
3
Department of Biology, University of Tor Vergata, Via della Ricerca Scientifica, 1-00173 Rome, Italy
*
Author to whom correspondence should be addressed.
Received: 7 March 2014 / Revised: 30 May 2014 / Accepted: 25 June 2014 / Published: 1 July 2014
(This article belongs to the Section Biosensors)
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Abstract

Flex sensors can be usefully adopted as mechanical-electrical transducers to measure human joint movements, since their electrical resistance varies proportionally to the angle assumed by the joint under measure. Over time, these sensors have been investigated in terms of mechanical and electrical behavior, but no reports have detailed the possibility of their adoption not just on top but under the human skin of the joint. To this aim, our work investigated in vitro the pyrogenic potential and cytotoxicity of some commercially available flex sensors as a first step toward the necessary requirements regarding their biocompatibility, to predict possible foreign body reactions when used in vivo. Results demonstrated that some specific flex sensors satisfy such requirements.
Keywords: flex sensors; pyrogenic potential; cytotoxicity; biocompatibility; human joints flex sensors; pyrogenic potential; cytotoxicity; biocompatibility; human joints
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Saggio, G.; Bianchi, L.; Castelli, S.; Santucci, M.B.; Fraziano, M.; Desideri, A. In Vitro Analysis of Pyrogenicity and Cytotoxicity Profiles of Flex Sensors to be Used to Sense Human Joint Postures. Sensors 2014, 14, 11672-11681.

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