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Sensors 2013, 13(3), 3975-3985; doi:10.3390/s130303975
Article

Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties

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Received: 30 January 2013; in revised form: 5 March 2013 / Accepted: 10 March 2013 / Published: 20 March 2013
(This article belongs to the Section Biosensors)
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Abstract: Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS) properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [pSB1075] and Chromobacterium violaceum CV026. It was found that the extracts of these three plants have anti-QS ability. Interestingly, the hexane, chloroform and methanol extracts from P. betle showed the most potent anti-QS activity as judged by the bioassays. Since there is a variety of plants that serve as food sources in Malaysia that have yet to be tested for anti-QS activity, future work should focus on identification of these plants and isolation of the anti-QS compounds.
Keywords: natural products; Pseudomonas aeruginosa; pathogenicity; pyocyanin; quorum sensing; quorum quenching; swarming; violacein; virulence natural products; Pseudomonas aeruginosa; pathogenicity; pyocyanin; quorum sensing; quorum quenching; swarming; violacein; virulence
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Tan, L.Y.; Yin, W.-F.; Chan, K.-G. Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties. Sensors 2013, 13, 3975-3985.

AMA Style

Tan LY, Yin W-F, Chan K-G. Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties. Sensors. 2013; 13(3):3975-3985.

Chicago/Turabian Style

Tan, Li Y.; Yin, Wai-Fong; Chan, Kok-Gan. 2013. "Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties." Sensors 13, no. 3: 3975-3985.



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