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A Multi-Parameter Decoupling Method with a Lamb Wave Sensor for Improving the Selectivity of Label-Free Liquid Detection†
Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China
Institute FEMTO-ST, CNRS, Université de Franche-Comté, Besançon 25044, France
† Earlier version of this paper appears in the 16th International Conference on Solid-State Sensors, Actuators and Microsystems, Beijing, China, 5–9 June 2011.
* Author to whom correspondence should be addressed.
Received: 17 June 2012; in revised form: 17 July 2012 / Accepted: 24 July 2012 / Published: 31 July 2012
Abstract: In this paper, a liquid multi-parameter decoupling method with only one Lamb wave sensor is presented. In a Lamb wave sensor, antisymmetric modes (A01 mode for low frequency, A03 mode for high frequency) and symmetric modes (S0 mode) are used to detect multiple parameters of a liquid, such as its density, sound velocity, and viscosity. We found they can play very different roles in the detections. For example, the A01 mode is very sensitive to the liquid’s density but the A03 mode is sensitive to the sound velocity. Here, the A0 mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S0 mode. This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.
Keywords: Lamb wave sensor; density; sound velocity; viscosity; determination of multi-parameters
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Zhou, L.; Wu, Y.; Xuan, M.; Manceau, J.-F.; Bastien, F. A Multi-Parameter Decoupling Method with a Lamb Wave Sensor for Improving the Selectivity of Label-Free Liquid Detection. Sensors 2012, 12, 10369-10380.
Zhou L, Wu Y, Xuan M, Manceau J-F, Bastien F. A Multi-Parameter Decoupling Method with a Lamb Wave Sensor for Improving the Selectivity of Label-Free Liquid Detection. Sensors. 2012; 12(8):10369-10380.
Zhou, Lianqun; Wu, Yihui; Xuan, Ming; Manceau, Jean-François; Bastien, François. 2012. "A Multi-Parameter Decoupling Method with a Lamb Wave Sensor for Improving the Selectivity of Label-Free Liquid Detection." Sensors 12, no. 8: 10369-10380.