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A Portable and Power-Free Microﬂuidic Device for Rapid and Sensitive Lead (Pb2+) Detection
Laboratory of Advanced Materials, Fudan University, 2205 Songhu Road, Shanghai 200438, China
Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
Shanghai Institute of Measurement and Testing Technology, Shanghai 201203, China
* Authors to whom correspondence should be addressed.
Received: 29 May 2012; in revised form: 6 June 2012 / Accepted: 2 July 2012 / Published: 10 July 2012
Abstract: A portable and power-free microﬂuidic device was designed for rapid and sensitive detection of lead (Pb2+). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb2+ for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten μM Pb2+ was successfully detected.
Keywords: gold nanoparticles; Pb2+; 11-mercaptoundecanoic acid; microfluidic chip
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Cite This Article
MDPI and ACS Style
Fan, C.; He, S.; Liu, G.; Wang, L.; Song, S. A Portable and Power-Free Microﬂuidic Device for Rapid and Sensitive Lead (Pb2+) Detection. Sensors 2012, 12, 9467-9475.
Fan C, He S, Liu G, Wang L, Song S. A Portable and Power-Free Microﬂuidic Device for Rapid and Sensitive Lead (Pb2+) Detection. Sensors. 2012; 12(7):9467-9475.
Fan, Chunhui; He, Shijiang; Liu, Gang; Wang, Lianhui; Song, Shiping. 2012. "A Portable and Power-Free Microﬂuidic Device for Rapid and Sensitive Lead (Pb2+) Detection." Sensors 12, no. 7: 9467-9475.