Sensors 2012, 12(2), 2236-2254; doi:10.3390/s120202236
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Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform

Department of Anesthesiology, Yale University School of Medicine, 333 Cedar Street, P.O. Box 208051, New Haven, CT 06520, USA
* Author to whom correspondence should be addressed.
Received: 13 December 2011; in revised form: 7 February 2012 / Accepted: 8 February 2012 / Published: 16 February 2012
(This article belongs to the Special Issue Optical Sensors in Medicine)
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Abstract: The photoplethysmographic waveform sits at the core of the most used, and arguably the most important, clinical monitor, the pulse oximeter. Interestingly, the pulse oximeter was discovered while examining an artifact during the development of a noninvasive cardiac output monitor. This article will explore the response of the pulse oximeter waveform to various modes of ventilation. Modern digital signal processing is allowing for a re-examination of this ubiquitous signal. The effect of ventilation on the photoplethysmographic waveform has long been thought of as a source of artifact. The primary goal of this article is to improve the understanding of the underlying physiology responsible for the observed phenomena, thereby encouraging the utilization of this understanding to develop new methods of patient monitoring. The reader will be presented with a review of respiratory physiology followed by numerous examples of the impact of ventilation on the photoplethysmographic waveform.
Keywords: clinical monitoring; photoplethysmographic waveform; respiratory physiology; pulse oximeter waveform

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MDPI and ACS Style

Alian, A.A.; Shelley, K.H. Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform. Sensors 2012, 12, 2236-2254.

AMA Style

Alian AA, Shelley KH. Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform. Sensors. 2012; 12(2):2236-2254.

Chicago/Turabian Style

Alian, Aymen A.; Shelley, Kirk H. 2012. "Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform." Sensors 12, no. 2: 2236-2254.

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