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CdTe and CdSe Quantum Dots Cytotoxicity: A Comparative Study on Microorganisms
Laboratório de Biologia de Insetos, GBG, Universidade Federal Fluminense—UFF, Niterói, RJ, CEP: 24210-130, Brazil
Laboratório de Transmissores de Leishmanioses, Setor de Entomologia Médica e Forense, IOC-FIOCRUZ, Rio de Janeiro, RJ, CEP: 21040-360, Brazil
Laboratório de Aplicações Biomédicas de Lasers, Departamento de Eletrônica Quântica, Instituto de Física Gleb Wataghin, Universidade Estadual de Campinas, Campinas, SP, CEP: 13083-970, Brazil
Laboratório de Biologia Celular, IOC-FIOCRUZ, Rio de Janeiro, RJ, CEP: 21040-360, Brazil
* Author to whom correspondence should be addressed.
Received: 27 October 2011; in revised form: 26 November 2011 / Accepted: 9 December 2011 / Published: 15 December 2011
Abstract: Quantum dots (QDs) are colloidal semiconductor nanocrystals of a few nanometers in diameter, being their size and shape controlled during the synthesis. They are synthesized from atoms of group II–VI or III–V of the periodic table, such as cadmium telluride (CdTe) or cadmium selenium (CdSe) forming nanoparticles with fluorescent characteristics superior to current fluorophores. The excellent optical characteristics of quantum dots make them applied widely in the field of life sciences. Cellular uptake of QDs, location and translocation as well as any biological consequence, such as cytotoxicity, stimulated a lot of scientific research in this area. Several studies pointed to the cytotoxic effect against micoorganisms. In this mini-review, we overviewed the synthesis and optical properties of QDs, and its advantages and bioapplications in the studies about microorganisms such as protozoa, bacteria, fungi and virus.
Keywords: quantum dots; citotoxicity; Trypanosoma cruzi; bacteria; microorganisms
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Gomes, S.A.; Vieira, C.S.; Almeida, D.B.; Santos-Mallet, J.R.; Menna-Barreto, R.F.S.; Cesar, C.L.; Feder, D. CdTe and CdSe Quantum Dots Cytotoxicity: A Comparative Study on Microorganisms. Sensors 2011, 11, 11664-11678.
Gomes SA, Vieira CS, Almeida DB, Santos-Mallet JR, Menna-Barreto RFS, Cesar CL, Feder D. CdTe and CdSe Quantum Dots Cytotoxicity: A Comparative Study on Microorganisms. Sensors. 2011; 11(12):11664-11678.
Gomes, Suzete A.O.; Vieira, Cecilia Stahl; Almeida, Diogo B.; Santos-Mallet, Jacenir R.; Menna-Barreto, Rubem F. S.; Cesar, Carlos L.; Feder, Denise. 2011. "CdTe and CdSe Quantum Dots Cytotoxicity: A Comparative Study on Microorganisms." Sensors 11, no. 12: 11664-11678.