Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles

doi:10.3390/s100706477

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Sensors 2010, 10(7), 6477-6487; doi:10.3390/s100706477

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Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles

Miao Wan^1,2, Pengfei Luo¹, Jiayi Jin³, Jiong Xing¹, Zhiyong Wang^1,* and Stephen T. C. Wong^1,*

¹ Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA ² College of Math and Physics, China University of Geoscience, Wuhan 430074, China ³ Department of Electrical & Computer Engineering, Texas A&M University, College Station, Texas 77844, USA

* Authors to whom correspondence should be addressed.

Received: 11 May 2010; in revised form: 8 June 2010 / Accepted: 21 June 2010 / Published: 1 July 2010

(This article belongs to the Section Biosensors)

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Abstract: An nm-thickness composite gold thin film consisting of gold nanoparticles and polyelectrolytes is fabricated through ionic self-assembled multilayers (ISAM) technique and is deposited on end-faces of optical fibers to construct localized surface plasmon resonance (LSPR) fiber probes. We demonstrate that the LSPR spectrum induced by ISAM gold films can be fine-tuned through the ISAM procedure. We investigate variations of reflection spectra of the probe with respect to the layer-by-layer adsorption of ISAMs onto end-faces of fibers, and study the spectral variation mechanism. Finally, we demonstrated using this fiber probe to detect the biotin-streptavidin bioconjugate pair. ISAM adsorbed on optical fibers potentially provides a simple, fast, robust, and low-cost, platform for LSPR biosensing applications.

Keywords: localized surface plasmon resonance; ionic self-assembled multilayers; fiber optics; biosensors

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MDPI and ACS Style

Wan, M.; Luo, P.; Jin, J.; Xing, J.; Wang, Z.; Wong, S.T.C. Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles. Sensors 2010, 10, 6477-6487.

AMA Style

Wan M., Luo P., Jin J., Xing J., Wang Z., Wong S.T.C. Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles. Sensors. 2010; 10(7):6477-6487.

Chicago/Turabian Style

Wan, Miao; Luo, Pengfei; Jin, Jiayi; Xing, Jiong; Wang, Zhiyong; Wong, Stephen T. C. 2010. "Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles." Sensors 10, no. 7: 6477-6487.

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