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Sensors 2010, 10(7), 6477-6487; https://doi.org/10.3390/s100706477

Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles

1
Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA
2
College of Math and Physics, China University of Geoscience, Wuhan 430074, China
3
Department of Electrical & Computer Engineering, Texas A&M University, College Station, Texas 77844, USA
*
Authors to whom correspondence should be addressed.
Received: 11 May 2010 / Revised: 8 June 2010 / Accepted: 21 June 2010 / Published: 1 July 2010
(This article belongs to the Section Biosensors)
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Abstract

An nm-thickness composite gold thin film consisting of gold nanoparticles and polyelectrolytes is fabricated through ionic self-assembled multilayers (ISAM) technique and is deposited on end-faces of optical fibers to construct localized surface plasmon resonance (LSPR) fiber probes. We demonstrate that the LSPR spectrum induced by ISAM gold films can be fine-tuned through the ISAM procedure. We investigate variations of reflection spectra of the probe with respect to the layer-by-layer adsorption of ISAMs onto end-faces of fibers, and study the spectral variation mechanism. Finally, we demonstrated using this fiber probe to detect the biotin-streptavidin bioconjugate pair. ISAM adsorbed on optical fibers potentially provides a simple, fast, robust, and low-cost, platform for LSPR biosensing applications. View Full-Text
Keywords: localized surface plasmon resonance; ionic self-assembled multilayers; fiber optics; biosensors localized surface plasmon resonance; ionic self-assembled multilayers; fiber optics; biosensors
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Wan, M.; Luo, P.; Jin, J.; Xing, J.; Wang, Z.; Wong, S.T.C. Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles. Sensors 2010, 10, 6477-6487.

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