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Sensors 2010, 10(4), 3585-3596; doi:10.3390/s100403585

Optical Fiber LSPR Biosensor Prepared by Gold Nanoparticle Assembly on Polyelectrolyte Multilayer

1
State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, China
2
Department of Materials Science, Jilin University, Changchun 130012, China
*
Author to whom correspondence should be addressed.
Received: 27 January 2010 / Revised: 26 February 2010 / Accepted: 8 March 2010 / Published: 8 April 2010
(This article belongs to the Section Biosensors)
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Abstract

This article provides a novel method of constructing an optical fiber localized surface plasmon resonance (LSPR) biosensor. A gold nanoparticle (NP) assembled film as the sensing layer was built on the polyelectrolyte (PE) multilayer modified sidewall of an unclad optical fiber. By using a trilayer PE structure, we obtained a monodisperse gold NP assembled film. The preparation procedure for this LSPR sensor is simple and time saving. The optical fiber LSPR sensor has higher sensitivity and outstanding reproducibility. The higher anti-interference ability for response to an antibody makes it a promising method in application as a portable immuno-sensor.
Keywords: localized surface plasmon resonance (LSPR); metal nanoparticle; optical fiber sensor; self-assembly; immuno detection localized surface plasmon resonance (LSPR); metal nanoparticle; optical fiber sensor; self-assembly; immuno detection
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Shao, Y.; Xu, S.; Zheng, X.; Wang, Y.; Xu, W. Optical Fiber LSPR Biosensor Prepared by Gold Nanoparticle Assembly on Polyelectrolyte Multilayer. Sensors 2010, 10, 3585-3596.

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