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Sensors 2010, 10(11), 9630-9646; doi:10.3390/s101109630
Review

Theory and Applications of Surface Plasmon Resonance, Resonant Mirror, Resonant Waveguide Grating, and Dual Polarization Interferometry Biosensors

1
 and 2,*
1 Department of Structural Biology, University of Pittsburgh, BST3 10017, 3501 Fifth Ave, Pittsburgh PA, 15213, USA 2 Departments of Pharmaceutical Sciences and of Chemistry, University of Pittsburgh, BST3 10017, 3501 Fifth Ave, Pittsburgh PA, 15213, USA
* Author to whom correspondence should be addressed.
Received: 23 August 2010 / Revised: 13 September 2010 / Accepted: 28 October 2010 / Published: 1 November 2010
(This article belongs to the Section Biosensors)
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Abstract

Biosensors have been used extensively in the scientific community for several purposes, most notably to determine association and dissociation kinetics, protein-ligand, protein-protein, or nucleic acid hybridization interactions. A number of different types of biosensors are available in the field, each with real or perceived benefits over the others. This review discusses the basic theory and operational arrangements of four commercially available types of optical biosensors: surface plasmon resonance, resonant mirror, resonance waveguide grating, and dual polarization interferometry. The different applications these techniques offer are discussed from experiments and results reported in recently published literature. Additionally, recent advancements or modifications to the current techniques are also discussed.
Keywords: optical biosensor; surface plasmon resonance; resonant mirror; resonance waveguide grating; dual polarization interferometry optical biosensor; surface plasmon resonance; resonant mirror; resonance waveguide grating; dual polarization interferometry
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Daghestani, H.N.; Day, B.W. Theory and Applications of Surface Plasmon Resonance, Resonant Mirror, Resonant Waveguide Grating, and Dual Polarization Interferometry Biosensors. Sensors 2010, 10, 9630-9646.

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