Diversity 2013, 5(3), 627-640; doi:10.3390/d5030627
Article

Untangling the Genetic Basis of Fibrolytic Specialization by Lachnospiraceae and Ruminococcaceae in Diverse Gut Communities

Received: 17 May 2013; in revised form: 21 June 2013 / Accepted: 26 June 2013 / Published: 9 August 2013
(This article belongs to the Special Issue Microbial Ecology and Diversity)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The Lachnospiraceae and Ruminococcaceae are two of the most abundant families from the order Clostridiales found in the mammalian gut environment, and have been associated with the maintenance of gut health. While they are both diverse groups, they share a common role as active plant degraders. By comparing the genomes of the Lachnospiraceae and Ruminococcaceae with the Clostridiaceae, a more commonly free-living group, we identify key carbohydrate-active enzymes, sugar transport mechanisms, and metabolic pathways that distinguish these two commensal groups as specialists for the degradation of complex plant material.
Keywords: Clostridiales; Ruminococcaceae; Lachnospiraceae; carbohydrate-active enzymes; comparative genomics; plant degradation
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MDPI and ACS Style

Biddle, A.; Stewart, L.; Blanchard, J.; Leschine, S. Untangling the Genetic Basis of Fibrolytic Specialization by Lachnospiraceae and Ruminococcaceae in Diverse Gut Communities. Diversity 2013, 5, 627-640.

AMA Style

Biddle A, Stewart L, Blanchard J, Leschine S. Untangling the Genetic Basis of Fibrolytic Specialization by Lachnospiraceae and Ruminococcaceae in Diverse Gut Communities. Diversity. 2013; 5(3):627-640.

Chicago/Turabian Style

Biddle, Amy; Stewart, Lucy; Blanchard, Jeffrey; Leschine, Susan. 2013. "Untangling the Genetic Basis of Fibrolytic Specialization by Lachnospiraceae and Ruminococcaceae in Diverse Gut Communities." Diversity 5, no. 3: 627-640.

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