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Molbank 2017, 2017(3), M956; doi:10.3390/M956

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 4-Aminobutyrate Hydrochloride

1
Department of Pharmaceutical Chemistry, I.I. Mechnikov Odessa National University, Odessa 65026, Ukraine
2
SSI “Institute for Single Crystals”, National Academy of Sciences of Ukraine, Kharkiv 61001, Ukraine
3
“INTERCHEM SLC”, Odessa 65080, Ukraine
4
A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa 65080, Ukraine
5
Department of Organic and Pharmaceutical Technology, Odessa National Polytechnic University, Odessa 65044, Ukraine
*
Author to whom correspondence should be addressed.
Received: 29 July 2017 / Revised: 11 August 2017 / Accepted: 20 August 2017 / Published: 22 August 2017
(This article belongs to the Section Structure Determination)
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Abstract

The title ester (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 4-aminobutyrate hydrochloride was obtained in 96% yield via Steglich esterification. The structure of the target compound was established by FTIR, HR-MS, 1H-NMR, 13C-NMR spectral analysis, and single crystal X-ray diffraction study. Single crystals of the title ester suitable for X-ray investigation were obtained by slow evaporation of the methanolic solution at room temperature. The purity of compound was assessed using HPLC coupled to mass spectrometry. View Full-Text
Keywords: terpene; l-menthol; ester; X-ray diffraction terpene; l-menthol; ester; X-ray diffraction
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Nesterkina, M.; Shishkina, S.; Maltsev, G.; Rakipov, I.; Kravchenko, I. (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 4-Aminobutyrate Hydrochloride. Molbank 2017, 2017, M956.

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