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Molbank 2015, 2015(2), M857; doi:10.3390/M857

Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

1
Department of Chemistry, Durham University, South Road, Durham DH1 3LE, UK
2
Syngenta CP R&D Chemistry, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK
*
Author to whom correspondence should be addressed.
Received: 7 April 2015 / Revised: 29 April 2015 / Accepted: 4 May 2015 / Published: 6 May 2015
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Abstract

This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note. View Full-Text
Keywords: thiazole; oxidation product; heterocycles thiazole; oxidation product; heterocycles
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Mallia, C.J.; Englert, L.; Walter, G.C.; Baxendale, I.R. Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate. Molbank 2015, 2015, M857.

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