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Molbank 2012, 2012(4), M781; doi:10.3390/M781
Short Note

2-[2-(Aziridin-1-yl)ethyl]-5,5-dimethyl-2,5-dihydro-4H-benzo [e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part IV)

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Received: 27 June 2012 / Accepted: 27 September 2012 / Published: 1 October 2012
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Abstract

An aziridine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.
Keywords: pyrrole; DNA-alkylation; anticancer pyrrole; DNA-alkylation; anticancer
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Spreitzer, H.; Puschmann, C. 2-[2-(Aziridin-1-yl)ethyl]-5,5-dimethyl-2,5-dihydro-4H-benzo [e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part IV). Molbank 2012, 2012, M781.

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