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Molbank 2011, 2011(2), M724; doi:10.3390/M724

Short Note

4-(3,5-Dibromo-4-hydroxyphenyl)-3-butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine

Zhen Wang and Qingjian Liu*

Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, College of Chemistry, Shandong Normal University, Jinan 250014, China

* Author to whom correspondence should be addressed.

Received: 2 April 2011 / Accepted: 15 April 2011 / Published: 26 April 2011

Download PDF Full-Text [122 KB, uploaded 26 April 2011 16:45 CEST]

Abstract: One-pot two-step Hantzsch synthesis of 4-(3,5-dibromo-4-hydroxyphenyl)-3- butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine under solvent- and catalyst-free conditions promoted with microwave irradiation is presented.

Keywords: 1,4-Dihydropyridines; Hantzsch reaction; microwave irradiation; solvent- and catalyst-free conditions

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