2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I)

doi:10.3390/M651

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Molbank 2010, 2010(1), M651; doi:10.3390/M651

Short Note

2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I)

Helmut Spreitzer* and Christiane Puschmann

Department of Drug and Natural Product Synthesis, Faculty of Life Sciences, University of Vienna, Althanstraße 14, A- 1090 Vienna, Austria

* Author to whom correspondence should be addressed.

Received: 4 December 2009 / Accepted: 12 January 2010 / Published: 22 January 2010

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Abstract: A bis(chloroethyl)amine containing side chain is attached to an oxonaphthalene-annelated pyrrol in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.

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Cite This Article

MDPI and ACS Style

Spreitzer, H.; Puschmann, C. 2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I). Molbank 2010, 2010, M651.

AMA Style

Spreitzer H, Puschmann C. 2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I). Molbank. 2010; 2010(1):M651.

Chicago/Turabian Style

Spreitzer, Helmut; Puschmann, Christiane. 2010. "2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I)." Molbank 2010, no. 1: M651.

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