Next Article in Journal
6-Oxo-3-phenyl-5,6-dihydropyridazine-1(4H)-carbohydrazide
Previous Article in Journal
5-(3-Nitrophenyl)-3-phenyl-4,5-dihydro-1H-pyrazole-1-carbaldehyde
Molbank 2010, 2010(1), M651; doi:10.3390/M651
Short Note

2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I)

*  and
Department of Drug and Natural Product Synthesis, Faculty of Life Sciences, University of Vienna, Althanstra├če 14, A- 1090 Vienna, Austria
* Author to whom correspondence should be addressed.
Received: 4 December 2009 / Accepted: 12 January 2010 / Published: 22 January 2010
Download PDF [77 KB, uploaded 22 January 2010]

Abstract

A bis(chloroethyl)amine containing side chain is attached to an oxonaphthalene-annelated pyrrol in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Spreitzer, H.; Puschmann, C. 2-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part I). Molbank 2010, 2010, M651.

View more citation formats

Supplements

Article Metrics

Comments

Citing Articles

[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert