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Int. J. Mol. Sci. 2008, 9(8), 1472-1488; doi:10.3390/ijms9081472

Muscle Contraction and Force: the Importance of an Ancillary Network, Nutrient Supply and Waste Removal

1
Department of Food Science, Faculty of Life Sciences, Copenhagen University, Frederiksberg C, Denmark
2
Department of Cell & Organism Biology, Lund University, Lund, Sweden
3
Department of Animal & Veterinary Basic Science, Faculty of Life Sciences, Copenhagen University, Frederiksberg C, Denmark
*
Author to whom correspondence should be addressed.
Received: 30 May 2008 / Revised: 11 July 2008 / Accepted: 4 August 2008 / Published: 20 August 2008
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Abstract

Muscle contraction studies often focus solely on myofibres and the proteins known to be involved in the processes of sarcomere shortening and cross-bridge cycling, but skeletal muscle also comprises a very elaborate ancillary network of capillaries, which not only play a vital role in terms of nutrient delivery and waste product removal, but are also tethered to surrounding fibres by collagen ”wires”. This paper therefore addresses aspects of the ancillary network of skeletal muscle at both a microscopic and functional level in order to better understand its role holistically as a considerable contributor to force transfer within muscular tissue.
Keywords: Collagen; muscle performance; fatigue; capillary network. Collagen; muscle performance; fatigue; capillary network.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Brüggemann, D.A.; Risbo, J.; Pierzynowski, S.G.; Harrison, A.P. Muscle Contraction and Force: the Importance of an Ancillary Network, Nutrient Supply and Waste Removal. Int. J. Mol. Sci. 2008, 9, 1472-1488.

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