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Water and Muscle Contraction
AbstractThe interaction between water and the protein of the contractile machinery as well as the tendency of these proteins to form geometrically ordered structures provide a link between water and muscle contraction. Protein osmotic pressure is strictly related to the chemical potential of the contractile proteins, to the stiffness of muscle structures and to the viscosity of the sliding of the thin over the thick filaments. Muscle power output and the steady rate of contraction are linked by modulating a single parameter, a viscosity coefficient. Muscle operation is characterized by working strokes of much shorter length and much quicker than in the classical model. As a consequence the force delivered and the stiffness attained by attached cross-bridges is much larger than usually believed.
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Grazi, E. Water and Muscle Contraction. Int. J. Mol. Sci. 2008, 9, 1435-1452.View more citation formats
Grazi E. Water and Muscle Contraction. International Journal of Molecular Sciences. 2008; 9(8):1435-1452.Chicago/Turabian Style
Grazi, Enrico. 2008. "Water and Muscle Contraction." Int. J. Mol. Sci. 9, no. 8: 1435-1452.