Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR

doi:10.3390/i8070705

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Int. J. Mol. Sci. 2007, 8(7), 705-713; doi:10.3390/i8070705

Communication

Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR

Zhiqiang Liang ¹, Ruojun Lao ², Jing Wang ¹, Yongbiao Liu ³, Lihua Wang ², Qing Huang ², Shiping Song ²^,* , Genxi Li ¹^,* and Chunhai Fan ²

¹ Department of Biochemistry, Nanjing University, Nanjing 210093, P. R. China ² Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, P. R. China ³ The People’s Hospital of Jiangsu Province, Nanjing 210029, P. R. China

* Authors to whom correspondence should be addressed.

Received: 31 May 2007; in revised form: 29 June 2007 / Accepted: 13 July 2007 / Published: 23 July 2007

(This article belongs to the Special Issue Nucleic Acid Derivatives in Emerging Technologies)

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Abstract: Carbon nanotubes (CNTs) can be effectively dispersed and functionalized bywrapping with long single-stranded DNA (ssDNA) synthesized by asymmetric PCR. ThessDNA-CNTs attached on surface of glass carbon electrode made it possible forelectrochemical analysis and sensing, which was demonstrated by reduction of H₂O₂ onhemoglobin/ssDNA-CNTs modified electrodes. This research showed the potentialapplication of DNA-functionalised CNTs in construction of future electrochemicalbiosensors.

Keywords: Carbon nanotubes (CNTs); single-stranded DNA (ssDNA); asymmetric PCR; electrochemical biosensor

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Cite This Article

MDPI and ACS Style

Liang, Z.; Lao, R.; Wang, J.; Liu, Y.; Wang, L.; Huang, Q.; Song, S.; Li, G.; Fan, C. Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR. Int. J. Mol. Sci. 2007, 8, 705-713.

AMA Style

Liang Z., Lao R., Wang J., Liu Y., Wang L., Huang Q., Song S., Li G., Fan C. Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR. International Journal of Molecular Sciences. 2007; 8(7):705-713.

Chicago/Turabian Style

Liang, Zhiqiang; Lao, Ruojun; Wang, Jing; Liu, Yongbiao; Wang, Lihua; Huang, Qing; Song, Shiping; Li, Genxi; Fan, Chunhai. 2007. "Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR." Int. J. Mol. Sci. 8, no. 7: 705-713.

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