Next Article in Journal
Efficient Gene Transfection into Mammalian Cells Mediated by Cross-linked Polyethylenimine
Previous Article in Journal
Interactions between Endostatin and Vascular Endothelial Growth Factor (VEGF) and Inhibition of Choroidal Neovascularization
Article Menu

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2007, 8(2), 70-80; doi:10.3390/i8020070

Microwave-Assisted Synthesis of Phenothiazine and Qinoline Derivatives

“Babeș-Bolyai” University, Faculty of Chemistry and Chemical Engineering, Organic Chemistry Department, Cluj-Napoca, Romania
INCDTIM-Cluj-Napoca, Romania
Institute of Organic Chemistry, National NMR Laboratory, Bucharest, Romania
Universitée de la Mediteranée, Faculté de Pharmacie, Marseille, France
Author to whom correspondence should be addressed.
Received: 27 October 2006 / Accepted: 12 February 2007 / Published: 13 February 2007
(This article belongs to the Section Physical Chemistry, Theoretical and Computational Chemistry)
View Full-Text   |   Download PDF [85 KB, uploaded 19 June 2014]   |  


Application of a dynamic microwave power system in the chemical synthesis ofsome phenothiazine and quinoline derivatives is described. Heterocyclic ring formation,aromatic nucleophilic substitution and heterocyclic aldehydes/ketones condensationreactions were performed on solid support, or under solvent free reaction conditions. Themicrowave-assisted Duff formylation of phenothiazine was achieved. Comparison ofmicrowave-assisted synthesis with the conventional synthetic methods demonstratesadvantages related to shorter reaction times and in some cases better reaction yields. View Full-Text
Keywords: MAOS; Quinoline; Pyrido[3,2-g]quinoline; Phenothiazine; formylation MAOS; Quinoline; Pyrido[3,2-g]quinoline; Phenothiazine; formylation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Găină, L.; Cristea, C.; Moldovan, C.; Porumb, D.; Surducan, E.; Deleanu, C.; Mahamoud, A.; Barbe, J.; Silberg, I.A. Microwave-Assisted Synthesis of Phenothiazine and Qinoline Derivatives. Int. J. Mol. Sci. 2007, 8, 70-80.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top