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Int. J. Mol. Sci. 2007, 8(2), 70-80; doi:10.3390/i8020070
Article

Microwave-Assisted Synthesis of Phenothiazine and Qinoline Derivatives

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Received: 27 October 2006; Accepted: 12 February 2007 / Published: 13 February 2007
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Abstract: Application of a dynamic microwave power system in the chemical synthesis ofsome phenothiazine and quinoline derivatives is described. Heterocyclic ring formation,aromatic nucleophilic substitution and heterocyclic aldehydes/ketones condensationreactions were performed on solid support, or under solvent free reaction conditions. Themicrowave-assisted Duff formylation of phenothiazine was achieved. Comparison ofmicrowave-assisted synthesis with the conventional synthetic methods demonstratesadvantages related to shorter reaction times and in some cases better reaction yields.
Keywords: MAOS; Quinoline; Pyrido[3,2-g]quinoline; Phenothiazine; formylation MAOS; Quinoline; Pyrido[3,2-g]quinoline; Phenothiazine; formylation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Găină, L.; Cristea, C.; Moldovan, C.; Porumb, D.; Surducan, E.; Deleanu, C.; Mahamoud, A.; Barbe, J.; Silberg, I.A. Microwave-Assisted Synthesis of Phenothiazine and Qinoline Derivatives. Int. J. Mol. Sci. 2007, 8, 70-80.

AMA Style

Găină L, Cristea C, Moldovan C, Porumb D, Surducan E, Deleanu C, Mahamoud A, Barbe J, Silberg IA. Microwave-Assisted Synthesis of Phenothiazine and Qinoline Derivatives. International Journal of Molecular Sciences. 2007; 8(2):70-80.

Chicago/Turabian Style

Găină, Luiza; Cristea, Castelia; Moldovan, Claudia; Porumb, Dan; Surducan, Emanoil; Deleanu, Calin; Mahamoud, Abdalah; Barbe, Jacques; Silberg, Ioan A. 2007. "Microwave-Assisted Synthesis of Phenothiazine and Qinoline Derivatives." Int. J. Mol. Sci. 8, no. 2: 70-80.


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