Next Article in Journal
Reproduction of Characteristics of Extracellular Matrices in Specific Longitudinal Depth Zone Cartilage within Spherical Organoids in Response to Changes in Osmotic Pressure
Previous Article in Journal
Melatonin Analogue Antiproliferative and Cytotoxic Effects on Human Prostate Cancer Cells
Article Menu
Issue 5 (May) cover image

Export Article

Open AccessReview
Int. J. Mol. Sci. 2018, 19(5), 1506; https://doi.org/10.3390/ijms19051506

Pharmacological Strategies for Manipulating Plant Ca2+ Signalling

1
Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, 9052 Ghent, Belgium
2
VIB Center for Plant Systems Biology, VIB, Technologiepark 927, 9052 Ghent, Belgium
3
Department of Biosciences, University of Milan, 20133 Milan, Italy
4
Instititute of Biophysics, Consiglio Nazionale delle Ricerche, 20133 Milan, Italy
5
Lab of Plant Growth Analysis, Ghent University Global Campus, Songdomunhwa-Ro, 119, Yeonsu-gu, Incheon 21985, Korea
*
Author to whom correspondence should be addressed.
Received: 27 April 2018 / Revised: 10 May 2018 / Accepted: 12 May 2018 / Published: 18 May 2018
(This article belongs to the Special Issue Calcium Signals in Plant Cells)
View Full-Text   |   Download PDF [341 KB, uploaded 18 May 2018]

Abstract

Calcium is one of the most pleiotropic second messengers in all living organisms. However, signalling specificity is encoded via spatio-temporally regulated signatures that act with surgical precision to elicit highly specific cellular responses. How this is brought about remains a big challenge in the plant field, in part due to a lack of specific tools to manipulate/interrogate the plant Ca2+ toolkit. In many cases, researchers resort to tools that were optimized in animal cells. However, the obviously large evolutionary distance between plants and animals implies that there is a good chance observed effects may not be specific to the intended plant target. Here, we provide an overview of pharmacological strategies that are commonly used to activate or inhibit plant Ca2+ signalling. We focus on highlighting modes of action where possible, and warn for potential pitfalls. Together, this review aims at guiding plant researchers through the Ca2+ pharmacology swamp. View Full-Text
Keywords: calcium; Ca2+ channel; Ca2+ ATPase; calmodulin; Ca2+ chelator; Ca2+ ionophore calcium; Ca2+ channel; Ca2+ ATPase; calmodulin; Ca2+ chelator; Ca2+ ionophore
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

De Vriese, K.; Costa, A.; Beeckman, T.; Vanneste, S. Pharmacological Strategies for Manipulating Plant Ca2+ Signalling. Int. J. Mol. Sci. 2018, 19, 1506.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top