Next Article in Journal
Novel Furocoumarin Derivatives Stimulate Melanogenesis in B16 Melanoma Cells by Up-Regulation of MITF and TYR Family via Akt/GSK3β/β-Catenin Signaling Pathways
Previous Article in Journal
Vesicular Axonal Transport is Modified In Vivo by Tau Deletion or Overexpression in Drosophila
Previous Article in Special Issue
Electrophoretic Deposition of Hydroxyapatite Film Containing Re-Doped MoS2 Nanoparticles
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2018, 19(3), 745; doi:10.3390/ijms19030745

Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication

Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford OX3 7LD, UK
Center for Biomaterials, Korea Institute of Science & Technology (KIST), Seoul 02792, Korea
Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Korea
Author to whom correspondence should be addressed.
Received: 15 November 2017 / Revised: 26 February 2018 / Accepted: 3 March 2018 / Published: 6 March 2018
(This article belongs to the Special Issue Novel Biomaterials for Tissue Engineering 2018)
View Full-Text   |   Download PDF [3295 KB, uploaded 6 March 2018]   |  


Electrospinning has been used for the fabrication of extracellular matrix (ECM)-mimicking fibrous scaffolds for several decades. Electrospun fibrous scaffolds provide nanoscale/microscale fibrous structures with interconnecting pores, resembling natural ECM in tissues, and showing a high potential to facilitate the formation of artificial functional tissues. In this review, we summarize the fundamental principles of electrospinning processes for generating complex fibrous scaffold geometries that are similar in structural complexity to the ECM of living tissues. Moreover, several approaches for the formation of three-dimensional fibrous scaffolds arranged in hierarchical structures for tissue engineering are also presented. View Full-Text
Keywords: electrospinning; nanofiber scaffolds; tissue engineering; extracellular matrix-mimicking geometries electrospinning; nanofiber scaffolds; tissue engineering; extracellular matrix-mimicking geometries

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Jun, I.; Han, H.-S.; Edwards, J.R.; Jeon, H. Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication. Int. J. Mol. Sci. 2018, 19, 745.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top