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Int. J. Mol. Sci. 2018, 19(1), 264; doi:10.3390/ijms19010264

Salvia Species as Sources of Natural Products with Antiprotozoal Activity

Institut für Pharmazeutische Biologie und Phytochemie (IPBP), University of Münster, PharmaCampus, Corrensstraße 48, D-48149 Münster, Germany
Author to whom correspondence should be addressed.
Received: 15 December 2017 / Revised: 5 January 2018 / Accepted: 11 January 2018 / Published: 16 January 2018
(This article belongs to the Section Bioactives and Nutraceuticals)
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Natural products from plants have been used since ancestral times to treat a wide variety of diseases worldwide. Plants of the genus Salvia (Sage) have been reported to be used for the prevention and treatment of various diseases and ailments. In particular, some Salvia species have been used in traditional medicine to treat diseases caused by protozoan parasites of the genera Trypanosoma, Leishmania and Plasmodium and scientific studies have demonstrated the activity of various isolated constituents from these plants against these pathogens. The current review attempts to give a critical overview of published information about the antiprotozoal activity of species of the genus Salvia and their chemical constituents. It is meant to give a unified overview of these results in order to avoid repetitions caused, e.g., by limited access to some primary reports, and to stimulate further research to possibly facilitate the development of new molecular leads against protozoal neglected tropical diseases (NTDs) based on Salvia constituents. View Full-Text
Keywords: Salvia; natural products; neglected tropical diseases (NTDs); Plasmodium; Leishmania; Trypanosoma; global health Salvia; natural products; neglected tropical diseases (NTDs); Plasmodium; Leishmania; Trypanosoma; global health

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Llurba-Montesino, N.; Schmidt, T.J. Salvia Species as Sources of Natural Products with Antiprotozoal Activity. Int. J. Mol. Sci. 2018, 19, 264.

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