Effects of Melatonin on Liver Injuries and Diseases
AbstractLiver injuries and diseases are serious health problems worldwide. Various factors, such as chemical pollutants, drugs, and alcohol, could induce liver injuries. Liver diseases involve a wide range of liver pathologies, including hepatic steatosis, fatty liver, hepatitis, fibrosis, cirrhosis, and hepatocarcinoma. Despite all the studies performed up to now, therapy choices for liver injuries and diseases are very few. Therefore, the search for a new treatment that could safely and effectively block or reverse liver injuries and diseases remains a priority. Melatonin is a well-known natural antioxidant, and has many bioactivities. There are numerous studies investigating the effects of melatonin on liver injuries and diseases, and melatonin could regulate various molecular pathways, such as inflammation, proliferation, apoptosis, metastasis, and autophagy in different pathophysiological situations. Melatonin could be used for preventing and treating liver injuries and diseases. Herein, we conduct a review summarizing the potential roles of melatonin in liver injuries and diseases, paying special attention to the mechanisms of action. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Zhang, J.-J.; Meng, X.; Li, Y.; Zhou, Y.; Xu, D.-P.; Li, S.; Li, H.-B. Effects of Melatonin on Liver Injuries and Diseases. Int. J. Mol. Sci. 2017, 18, 673.
Zhang J-J, Meng X, Li Y, Zhou Y, Xu D-P, Li S, Li H-B. Effects of Melatonin on Liver Injuries and Diseases. International Journal of Molecular Sciences. 2017; 18(4):673.Chicago/Turabian Style
Zhang, Jiao-Jiao; Meng, Xiao; Li, Ya; Zhou, Yue; Xu, Dong-Ping; Li, Sha; Li, Hua-Bin. 2017. "Effects of Melatonin on Liver Injuries and Diseases." Int. J. Mol. Sci. 18, no. 4: 673.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.