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Int. J. Mol. Sci. 2017, 18(2), 340; doi:10.3390/ijms18020340

Effect of Silver Diamine Fluoride and Potassium Iodide Treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration

1
Faculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China
2
Melbourne Dental School, University of Melbourne, Melbourne 3010, Australia
*
Author to whom correspondence should be addressed.
Academic Editor: Nick Hadjiliadis
Received: 10 January 2017 / Revised: 29 January 2017 / Accepted: 31 January 2017 / Published: 6 February 2017
(This article belongs to the Section Bioinorganic Chemistry)
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Abstract

This study investigated the effect of silver diamine fluoride (SDF) and potassium iodide (KI) treatment on secondary caries prevention and tooth discolouration in glass ionomer cement (GIC) restoration. Cervical GIC restorations were done on 30 premolars with: Group 1, SDF + KI; Group 2, SDF (positive control); Group 3, no treatment (negative control). After cariogenic biofilm challenge, the demineralisation of dentine adjacent to the restoration was evaluated using micro-computed tomography (micro-CT) and Fourier transform infrared (FTIR) spectroscopy. The colour of dentine adjacent to the restoration was assessed using CIELAB system at different time points. Total colour change (∆E) was calculated and was visible if ∆E > 3.7. Micro-CT showed the outer lesion depths for Groups 1, 2 and 3 were 91 ± 7 µm, 80 ± 7 µm and 119 ± 8 µm, respectively (p < 0.001; Group 2 < Group 1 < Group 3). FTIR found that there was a significant difference in amide I-to-hydrogen phosphate ratio among the three groups (p < 0.001; Group 2 < Group 1 < Group 3). ∆E of Groups 1, 2 and 3 after biofilm challenge were 22.5 ± 4.9, 70.2 ± 8.3 and 2.9 ± 0.9, respectively (p < 0.001; Group 3 < Group 1 < Group 2). SDF + KI treatment reduced secondary caries formation on GIC restoration, but it was not as effective as SDF treatment alone. Moreover, a perceptible staining on the restoration margin was observed, but the intensity of discolouration was less than that with solely SDF treatment. View Full-Text
Keywords: silver diamine fluoride; potassium iodide; secondary caries; glass ionomer; discolouration silver diamine fluoride; potassium iodide; secondary caries; glass ionomer; discolouration
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MDPI and ACS Style

Zhao, I.S.; Mei, M.L.; Burrow, M.F.; Lo, E.C.-M.; Chu, C.-H. Effect of Silver Diamine Fluoride and Potassium Iodide Treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration. Int. J. Mol. Sci. 2017, 18, 340.

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