Influenza A Virus M2 Protein: Roles from Ingress to Egress
AbstractInfluenza A virus (IAV) matrix protein 2 (M2) is among the smallest bona fide, hence extensively studied, ion channel proteins. The M2 ion channel activity is not only essential for virus replication, but also involved in modulation of cellular homeostasis in a variety of ways. It is also the target for ion channel inhibitors, i.e., anti-influenza drugs. Thus far, several studies have been conducted to elucidate its biophysical characteristics, structure-function relationships of the ion channel, and the M2-host interactome. In this review, we discuss M2 protein synthesis and assembly into an ion channel, its roles in IAV replication, and the pathophysiological impact on the host cell. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Manzoor, R.; Igarashi, M.; Takada, A. Influenza A Virus M2 Protein: Roles from Ingress to Egress. Int. J. Mol. Sci. 2017, 18, 2649.
Manzoor R, Igarashi M, Takada A. Influenza A Virus M2 Protein: Roles from Ingress to Egress. International Journal of Molecular Sciences. 2017; 18(12):2649.Chicago/Turabian Style
Manzoor, Rashid; Igarashi, Manabu; Takada, Ayato. 2017. "Influenza A Virus M2 Protein: Roles from Ingress to Egress." Int. J. Mol. Sci. 18, no. 12: 2649.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.