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Int. J. Mol. Sci. 2017, 18(1), 208; doi:10.3390/ijms18010208

Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging

1
Aelan Cell Technology, San Francisco, CA 94107, USA
2
Division of Plastic Surgery, University of California, San Diego, La Jolla, CA 92121, USA
*
Author to whom correspondence should be addressed.
Academic Editors: Adriano Piatelli and Barbara Zavan
Received: 25 October 2016 / Revised: 5 January 2017 / Accepted: 5 January 2017 / Published: 20 January 2017
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Abstract

Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation, migration, enzymatic reactions, and to equilibrate the regenerative demands of balanced tissue homeostasis. The identification of the mechanisms by which ADSCs accomplish these functions for dermatological rejuvenation and wound healing has great potential to identify novel targets for the treatment of disorders and combat aging. Herein, we review new insights into the role of adipose-derived stem cells in the maintenance of dermal and epidermal homeostasis, and recent advances in clinical applications of ADSCs related to dermatology. View Full-Text
Keywords: adipose-derived stem cells; skin homeostasis; dermis; epidermis; subcutaneous adipose depot; matrikines; aging; wound healing; clinical applications adipose-derived stem cells; skin homeostasis; dermis; epidermis; subcutaneous adipose depot; matrikines; aging; wound healing; clinical applications
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Gaur, M.; Dobke, M.; Lunyak, V.V. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging. Int. J. Mol. Sci. 2017, 18, 208.

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