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Int. J. Mol. Sci. 2017, 18(1), 193; doi:10.3390/ijms18010193

Anti-NMDA Receptor Encephalitis and Vaccination

Institute of Statistics, National Chiao Tung University, Hsinchu 30010, Taiwan
Academic Editor: Alfredo Ciccodicola
Received: 15 October 2016 / Revised: 10 January 2017 / Accepted: 13 January 2017 / Published: 18 January 2017
(This article belongs to the Special Issue Transcriptome Profiling in Human Diseases)
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Abstract

Anti-N-methyl-d-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune neurological disorder. The cause of this disease is often unknown, and previous studies revealed that it might be caused by a virus, vaccine or tumor. It occurs more often in females than in males. Several cases were reported to be related to vaccination such as the H1N1 vaccine and tetanus/diphtheria/pertussis and polio vaccines. In this study, we reported an anti-NMDA receptor encephalitis case that may be caused by Japanese encephalitis vaccination. To investigate the association between anti-NMDA receptor encephalitis and vaccination, we analyzed the phylogenetic relationship of the microRNAs, which significantly regulate these vaccine viruses or bacteria, and the phylogenetic relationship of these viruses and bacteria. This reveals that anti-NMDA receptor encephalitis may be caused by Japanese encephalitis vaccination, as well as H1N1 vaccination or tetanus/diphtheria/pertussis and polio vaccinations, from the phylogenetic viewpoint. View Full-Text
Keywords: anti-NMDA receptor encephalitis; Japanese encephalitis; microRNA; vaccination anti-NMDA receptor encephalitis; Japanese encephalitis; microRNA; vaccination
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Wang, H. Anti-NMDA Receptor Encephalitis and Vaccination. Int. J. Mol. Sci. 2017, 18, 193.

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