Next Article in Journal
Environmental Factors Associated with Altered Gut Microbiota in Children with Eczema: A Systematic Review
Next Article in Special Issue
Structural Analysis of Hand Drawn Bumblebee Bombus terrestris Silk
Previous Article in Journal
Signaling Pathways in Melanogenesis
Article Menu
Issue 7 (July) cover image

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2016, 17(7), 1142; doi:10.3390/ijms17071142

Silkworm Gut Fiber of Bombyx mori as an Implantable and Biocompatible Light-Diffusing Fiber

1
Department of Biotechnology, Instituto Murciano de Investigación y Desarrollo Agrario y Alimentario (IMIDA), Murcia 30150, Spain
2
Departamento de Electromagnetismo y Electrónica, Universidad de Murcia, Murcia 30003, Spain
3
Biomaterials & Tissue Engineering Unit & Orthopedic Surgery Service, V. Arrixaca University Hospital, Murcia 30120, Spain
4
Department of Health Sciences, UCAM-Catholic University of Murcia, Murcia 30107, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: John G. Hardy
Received: 14 June 2016 / Revised: 8 July 2016 / Accepted: 9 July 2016 / Published: 16 July 2016
(This article belongs to the Special Issue Silk-Based Materials: From Production to Characterization)
View Full-Text   |   Download PDF [10498 KB, uploaded 16 July 2016]   |  

Abstract

This work describes a new approach to the delivery of light in deeper tissues, through a silk filament that is implantable, biocompatible, and biodegradable. In the present work, silkworm gut fibers (SGFs) of Bombyx mori L., are made by stretching the silk glands. Morphological, structural, and optical properties of the fibers have been characterized and the stimulatory effect of red laser light diffused from the fiber was assayed in fibroblast cultures. SGFs are formed by silk fibroin (SF) mainly in a β-sheet conformation, a stable and non-soluble state in water or biological fluids. The fibers showed a high degree of transparency to visible and infrared radiation. Using a red laser (λ = 650 nm) as source, the light was efficiently diffused along the fiber wall, promoting a significant increment in the cell metabolism 5 h after the irradiation. SGFs have shown their excellent properties as light-diffusing optical fibers with a stimulatory effect on cells. View Full-Text
Keywords: silkworm gut fiber; biocompatibility; light-diffusing optical fiber; silk fibroin silkworm gut fiber; biocompatibility; light-diffusing optical fiber; silk fibroin
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Cenis, J.L.; Aznar-Cervantes, S.D.; Lozano-Pérez, A.A.; Rojo, M.; Muñoz, J.; Meseguer-Olmo, L.; Arenas, A. Silkworm Gut Fiber of Bombyx mori as an Implantable and Biocompatible Light-Diffusing Fiber. Int. J. Mol. Sci. 2016, 17, 1142.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top