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Int. J. Mol. Sci. 2016, 17(2), 235; doi:10.3390/ijms17020235

Herbal Medicine in Mexico: A Cause of Hepatotoxicity. A Critical Review

Liver Research Unit, Medica Sur Clinic & Foundation, 14050 Mexico City, Mexico
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Author to whom correspondence should be addressed.
Academic Editors: Rolf Teschke and Raúl J. Andrade
Received: 6 January 2016 / Revised: 26 January 2016 / Accepted: 26 January 2016 / Published: 15 February 2016
(This article belongs to the Special Issue Drug, Herb, and Dietary Supplement Hepatotoxicity)
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Abstract

In Mexico, herbal products are commonly used as therapeutic tools. The analysis of several publications reveals that there are dozens of different herbs and herbal products used for different reasons, some of which have been implicated in causing toxic liver disease. However, methodological aspects limit the attribution of causality, and the precise incidence and clinical manifestations of herb-induced liver injury have not been well characterized. This review outlines the history of traditional herbal medicine in Mexico, critically summarizes the mechanisms and adverse effects of commonly used herbal plants, and examines the regulatory issues regarding the legal use of these products. View Full-Text
Keywords: herbal medicine; herb-induced liver injury (HILI); drug-induced liver injury (DILI); hepatotoxicity; herbal drug supplements (HDS); adverse events; regulation herbal medicine; herb-induced liver injury (HILI); drug-induced liver injury (DILI); hepatotoxicity; herbal drug supplements (HDS); adverse events; regulation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Valdivia-Correa, B.; Gómez-Gutiérrez, C.; Uribe, M.; Méndez-Sánchez, N. Herbal Medicine in Mexico: A Cause of Hepatotoxicity. A Critical Review. Int. J. Mol. Sci. 2016, 17, 235.

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