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Int. J. Mol. Sci. 2016, 17(11), 1877; doi:10.3390/ijms17111877

Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome

1
GENYAL Platform on Nutrition and Health, IMDEA Food Institute, CEI UAM + CSIC, 28049 Madrid, Spain
2
Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain
3
CIBER Fisiopatología de la Obesidad y la Nutrición (CIBERobn), 28029 Madrid, Spain
*
Authors to whom correspondence should be addressed.
Academic Editor: Maurizio Battino
Received: 5 September 2016 / Revised: 7 October 2016 / Accepted: 31 October 2016 / Published: 10 November 2016
(This article belongs to the Special Issue Advances in Nutritional Epidemiology)
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Abstract

Metabolic syndrome (MetS) is established as the combination of central obesity and different metabolic disturbances, such as insulin resistance, hypertension and dyslipidemia. This cluster of factors affects approximately 10%–50% of adults worldwide and the prevalence has been increasing in epidemic proportions over the last years. Thus, dietary strategies to treat this heterogenic disease are under continuous study. In this sense, diets based on negative-energy-balance, the Mediterranean dietary pattern, n-3 fatty acids, total antioxidant capacity and meal frequency have been suggested as effective approaches to treat MetS. Furthermore, the type and percentage of carbohydrates, the glycemic index or glycemic load, and dietary fiber content are some of the most relevant aspects related to insulin resistance and impaired glucose tolerance, which are important co-morbidities of MetS. Finally, new studies focused on the molecular action of specific nutritional bioactive compounds with positive effects on the MetS are currently an objective of scientific research worldwide. The present review summarizes some of the most relevant dietary approaches and bioactive compounds employed in the treatment of the MetS to date. View Full-Text
Keywords: metabolic syndrome; dietary strategies; bioactive compounds metabolic syndrome; dietary strategies; bioactive compounds
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MDPI and ACS Style

de la Iglesia, R.; Loria-Kohen, V.; Zulet, M.A.; Martinez, J.A.; Reglero, G.; Ramirez de Molina, A. Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome. Int. J. Mol. Sci. 2016, 17, 1877.

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