miR-155: A Novel Target in Allergic Asthma
AbstractMicroRNAs (miRNAs), a class of small non-coding RNAs of 18–24 nucleotides in length, function to posttranscriptionally regulate protein expression. miR-155 was one of the first identified and, to date, the most studied miRNA, and has been linked to various cellular processes such as modulation of immune responses and oncogenesis. Previous studies have identified miR-155 as a crucial positive regulator of Th1 immune response in autoimmune diseases, but as a suppressor of Th2 immunity in allergic disorders. However, recent studies have found new evidence that miR-155 plays an indispensible role in allergic asthma. This review summarizes the recent findings with respect to miR-155 in immune responses and the underlying mechanisms responsible for miR-155-related allergic diseases, as well as the similarities between miR-155 and glucocorticoids in immunity. View Full-Text
- Supplementary File 1:
Supplementary (PDF, 108 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Zhou, H.; Li, J.; Gao, P.; Wang, Q.; Zhang, J. miR-155: A Novel Target in Allergic Asthma. Int. J. Mol. Sci. 2016, 17, 1773.
Zhou H, Li J, Gao P, Wang Q, Zhang J. miR-155: A Novel Target in Allergic Asthma. International Journal of Molecular Sciences. 2016; 17(10):1773.Chicago/Turabian Style
Zhou, Hong; Li, Junyao; Gao, Peng; Wang, Qi; Zhang, Jie. 2016. "miR-155: A Novel Target in Allergic Asthma." Int. J. Mol. Sci. 17, no. 10: 1773.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.