Next Article in Journal
A Dynamic Combinatorial Approach for Identifying Side Groups that Stabilize DNA-Templated Supramolecular Self-Assemblies
Previous Article in Journal
Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2015, 16(2), 3599-3608; doi:10.3390/ijms16023599

Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines

1,2
,
1
and
1,*
1
Department of Chemistry, Tsinghua University, Beijing 100084, China
2
National Engineering Laboratory for Rice and Byproduct Deep Processing, Central South University of Forestry and Technology, Changsha 410004, China
*
Author to whom correspondence should be addressed.
Academic Editor: Andreas Taubert
Received: 25 December 2014 / Accepted: 2 February 2015 / Published: 5 February 2015
(This article belongs to the Section Biomaterial Sciences)
View Full-Text   |   Download PDF [741 KB, uploaded 5 February 2015]   |  

Abstract

3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh2Cy)Cl. View Full-Text
Keywords: aldehydes; annulation; golden complex; propargyl amine; pyrazines aldehydes; annulation; golden complex; propargyl amine; pyrazines
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Su, J.; Liu, H.; Hua, R. Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines. Int. J. Mol. Sci. 2015, 16, 3599-3608.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top