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Int. J. Mol. Sci. 2015, 16(11), 27433-27449; doi:10.3390/ijms161126036

Prostate Cancer Stem Cells: Research Advances

Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, H. Jordana 19, 41-808 Zabrze, Poland
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Academic Editor: William Chi-shing Cho
Received: 5 September 2015 / Revised: 26 September 2015 / Accepted: 8 October 2015 / Published: 17 November 2015
(This article belongs to the Special Issue Molecular Classification of Human Cancer: Diagnosis and Treatment)
View Full-Text   |   Download PDF [604 KB, uploaded 17 November 2015]   |  

Abstract

Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease. View Full-Text
Keywords: cancer stem cell; prostate cancer; metastasis; castration-resistant prostate cancer cancer stem cell; prostate cancer; metastasis; castration-resistant prostate cancer
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Jaworska, D.; Król, W.; Szliszka, E. Prostate Cancer Stem Cells: Research Advances. Int. J. Mol. Sci. 2015, 16, 27433-27449.

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