Next Article in Journal
Quantification of Drug Transport Function across the MultipleResistance-Associated Protein 2 (Mrp2) in Rat Livers
Previous Article in Journal
Transfer RNA Methyltransferases from Thermoplasma acidophilum, a Thermoacidophilic Archaeon
Previous Article in Special Issue
When Isolated at Full Receptivity, in Vitro Fertilized Wheat (Triticum aestivum, L.) Egg Cells Reveal [Ca2+]cyt Oscillation of Intracellular Origin
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessReview
Int. J. Mol. Sci. 2015, 16(1), 114-134; doi:10.3390/ijms16010114

Transmembrane Signal Transduction in Oocyte Maturation and Fertilization: Focusing on Xenopus laevis as a Model Animal

Laboratory of Cell Signaling and Development, Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University, Kamigamo-motoyama, Kita-ku, Kyoto 603-8555, Japan
Academic Editor: Kenji Murata
Received: 24 October 2014 / Accepted: 15 December 2014 / Published: 23 December 2014
(This article belongs to the Special Issue Cellular and Molecular Mechanisms of Sperm-Egg Interaction)
View Full-Text   |   Download PDF [771 KB, uploaded 23 December 2014]   |  

Abstract

Fertilization is a cell biological phenomenon of crucial importance for the birth of new life in a variety of multicellular and sexual reproduction species such as algae, animal and plants. Fertilization involves a sequence of events, in which the female gamete “egg” and the male gamete “spermatozoon (sperm)” develop, acquire their functions, meet and fuse with each other, to initiate embryonic and zygotic development. Here, it will be briefly reviewed how oocyte cytoplasmic components are orchestrated to undergo hormone-induced oocyte maturation and sperm-induced activation of development. I then review how sperm-egg membrane interaction/fusion and activation of development in the fertilized egg are accomplished and regulated through egg coat- or egg plasma membrane-associated components, highlighting recent findings and future directions in the studies using Xenopus laevis as a model experimental animal. View Full-Text
Keywords: fertilization; gamete interaction and fusion; membrane microdomains; oocyte maturation; signaling crosstalk; Src; uroplakin III fertilization; gamete interaction and fusion; membrane microdomains; oocyte maturation; signaling crosstalk; Src; uroplakin III
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Sato, K.-I. Transmembrane Signal Transduction in Oocyte Maturation and Fertilization: Focusing on Xenopus laevis as a Model Animal. Int. J. Mol. Sci. 2015, 16, 114-134.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top