Int. J. Mol. Sci. 2014, 15(3), 4714-4732; doi:10.3390/ijms15034714
Review

Current Progress in Bioactive Ceramic Scaffolds for Bone Repair and Regeneration

1,†email, 2,†email, 1email, 1email, 1email, 1email, 1email, 1email, 1,3,* email and 4,* email
Received: 20 January 2014; in revised form: 19 February 2014 / Accepted: 10 March 2014 / Published: 18 March 2014
(This article belongs to the Section Material Sciences and Nanotechnology)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Bioactive ceramics have received great attention in the past decades owing to their success in stimulating cell proliferation, differentiation and bone tissue regeneration. They can react and form chemical bonds with cells and tissues in human body. This paper provides a comprehensive review of the application of bioactive ceramics for bone repair and regeneration. The review systematically summarizes the types and characters of bioactive ceramics, the fabrication methods for nanostructure and hierarchically porous structure, typical toughness methods for ceramic scaffold and corresponding mechanisms such as fiber toughness, whisker toughness and particle toughness. Moreover, greater insights into the mechanisms of interaction between ceramics and cells are provided, as well as the development of ceramic-based composite materials. The development and challenges of bioactive ceramics are also discussed from the perspective of bone repair and regeneration.
Keywords: bioactive ceramic; nanostructure; pore architecture; preparation technique; bone repair
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MDPI and ACS Style

Gao, C.; Deng, Y.; Feng, P.; Mao, Z.; Li, P.; Yang, B.; Deng, J.; Cao, Y.; Shuai, C.; Peng, S. Current Progress in Bioactive Ceramic Scaffolds for Bone Repair and Regeneration. Int. J. Mol. Sci. 2014, 15, 4714-4732.

AMA Style

Gao C, Deng Y, Feng P, Mao Z, Li P, Yang B, Deng J, Cao Y, Shuai C, Peng S. Current Progress in Bioactive Ceramic Scaffolds for Bone Repair and Regeneration. International Journal of Molecular Sciences. 2014; 15(3):4714-4732.

Chicago/Turabian Style

Gao, Chengde; Deng, Youwen; Feng, Pei; Mao, Zhongzheng; Li, Pengjian; Yang, Bo; Deng, Junjie; Cao, Yiyuan; Shuai, Cijun; Peng, Shuping. 2014. "Current Progress in Bioactive Ceramic Scaffolds for Bone Repair and Regeneration." Int. J. Mol. Sci. 15, no. 3: 4714-4732.

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