Int. J. Mol. Sci. 2014, 15(2), 2840-2857; doi:10.3390/ijms15022840
Review

Gram-Negative Flagella Glycosylation

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Received: 4 January 2014; in revised form: 20 January 2014 / Accepted: 27 January 2014 / Published: 19 February 2014
(This article belongs to the Special Issue Glycosylation and Glycoproteins)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Protein glycosylation had been considered as an eccentricity of a few bacteria. However, through advances in analytical methods and genome sequencing, it is now established that bacteria possess both N-linked and O-linked glycosylation pathways. Both glycosylation pathways can modify multiple proteins, flagellins from Archaea and Eubacteria being one of these. Flagella O-glycosylation has been demonstrated in many polar flagellins from Gram-negative bacteria and in only the Gram-positive genera Clostridium and Listeria. Furthermore, O-glycosylation has also been demonstrated in a limited number of lateral flagellins. In this work, we revised the current advances in flagellar glycosylation from Gram-negative bacteria, focusing on the structural diversity of glycans, the O-linked pathway and the biological function of flagella glycosylation.
Keywords: flagella; Gram-negative; glycosylation
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MDPI and ACS Style

Merino, S.; Tomás, J.M. Gram-Negative Flagella Glycosylation. Int. J. Mol. Sci. 2014, 15, 2840-2857.

AMA Style

Merino S, Tomás JM. Gram-Negative Flagella Glycosylation. International Journal of Molecular Sciences. 2014; 15(2):2840-2857.

Chicago/Turabian Style

Merino, Susana; Tomás, Juan M. 2014. "Gram-Negative Flagella Glycosylation." Int. J. Mol. Sci. 15, no. 2: 2840-2857.


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