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Int. J. Mol. Sci. 2013, 14(4), 6848-6862; doi:10.3390/ijms14046848

Effects of Dietary Conjugated Linoleic Acid and Biopolymer Encapsulation on Lipid Metabolism in Mice

Department of Bioresources and Food Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-701, Korea
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Received: 17 January 2013 / Revised: 11 March 2013 / Accepted: 19 March 2013 / Published: 26 March 2013
(This article belongs to the Section Biochemistry, Molecular and Cellular Biology)
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Abstract

Forty mice were randomly divided into four groups on the basis of the diet to be fed as follows: 5% (low) fat diet (T1: LF); 20% (high) fat diet (T2: HF); 20% fat containing 1% conjugated linoleic acid (CLA) (T3: HFC); and 20% fat containing 1% CLA with 0.5% biopolymers (T4: HFCB). The high-fat with CLA diet groups (HFC and HFCB) and the low-fat diet group (LF) tended to have lower body weights and total adipose tissue weights than those of the high-fat diet group (HF). Serum leptin and triglyceride were significantly lower in the high fat with CLA-fed groups (HFC and HFCB) and the low-fat diet group (LF) than those in the high-fat diet group (HF). It is noteworthy that the high-fat with CLA and biopolymers group (HFCB) showed the lowest serum triglyceride and cholesterol concentrations. In the high-fat-fed group (HF), voluntary travel distance as a measure of physical activity decreased after three weeks of feeding. However, the CLA-fed groups showed increased physical activity. The groups fed high-fat diets supplemented with CLA alone and with CLA and biopolymers had higher viscosity of small intestinal contents than that in the low- and high-fat dietary groups. View Full-Text
Keywords: conjugated linoleic acid; biopolymers encapsulation; energy expenditure; adipose tissue; lipid metabolism conjugated linoleic acid; biopolymers encapsulation; energy expenditure; adipose tissue; lipid metabolism
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Hur, S.J.; Kim, D.H.; Chun, S.C.; Lee, S.K. Effects of Dietary Conjugated Linoleic Acid and Biopolymer Encapsulation on Lipid Metabolism in Mice. Int. J. Mol. Sci. 2013, 14, 6848-6862.

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